Frequency:
- Apply the cream to the skin of your clean face once daily in the evening.
- Patients are instructed to start with applying 2-3x/week for a few weeks and then increase to once daily as tolerated.
Dosage:
- Use enough cream to cover the entire face but apply sparingly.
Preparation:
- First, wash and dry your face thoroughly.
- Apply a pea-sized amount of topical rapamycin and spread it out evenly across your face.
- Patients may choose to apply a hydrating moisturizer to help combat potential skin dryness.
- Some patients use the topical on other parts of their body such as hands, neck, back of arms, etc.
Symptoms to Monitor:
- Reduction in Fine Lines and Wrinkles: Over time, topical rapamycin may help reduce the appearance of fine lines and wrinkles by promoting collagen production and enhancing skin elasticity.
- Skin Texture and Firmness: Rapamycin can improve skin texture by promoting cellular turnover and reducing roughness, leading to smoother, firmer skin.
- Hyperpigmentation and Age Spots: Topical rapamycin may help reduce hyperpigmentation and age spots by inhibiting excess melanin production.
- Skin Hydration and Moisture Retention: While rapamycin isn’t a direct moisturizer, it can enhance the skin barrier’s function, potentially improving moisture retention.
- Redness and Inflammation: Rapamycin has anti-inflammatory properties, which may help reduce redness and inflammation, particularly in conditions like rosacea or eczema.
- Pore Size and Clarity: By regulating sebum production and improving skin cell turnover, rapamycin can help minimize the appearance of pores and reduce acne.
- Overall Skin Tone and Brightness: With continued use, topical rapamycin can lead to a more radiant and even skin tone, reducing dullness.
- Reduction in Actinic Keratoses or Precancerous Lesions: Rapamycin may reduce the appearance of actinic keratoses (precancerous skin lesions) and potentially prevent their progression to skin cancer.
- Reduction in Keritosis Pelaris (KP): Topical rapamycin may help reduce the keratin buildup that leads to the formation of bumps in keratosis pilaris. This can result in smoother skin over time.